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Clinical

The Clinical Services Group offers the following services:

Antimicrobial Discovery

  • Screen Optimization
  • Shaker Culture Fermentations
  • Soil Screening
  • Screening Structural Analogues

Invitro Antimicrobial Evaluations

  • Develop Culture Collection
  • Spectrum Determination
  • Strain Expansion Studies
  • Resistance Mechanisms [Enzymatic (β-lactamase), OMP, Active efflux, Target modification]
  • Develop Quantitative Bioassay(s)

Invivo Antimicrobial Evaluations

  • Efficacy studies
  • Pharmacokinetics
  • Adsorption, Distribution, Metabolism, and Elimination
  • Tissue Levels
  • Serum Protein Binding

Pre-Clinical Development

  • Develop standardized protocols for multiple site studies
  • Develop Standardized Susceptibility Tests
  • Develop Susceptibility Test Quality Control Limits
  • Resistance Development
  • Effect of Testing Conditions
  • Effect of Miscellaneous Factors
  • Post Antibiotic Effects

Clinical Trial and Post Market Approval Support

  • Technical Service and Laboratory Support
  • Collect and Characterize Isolates
  • Specialized Studies

Develop Technical Communications Documentation

  • Brochures
  • Publications and Presentations
  • Regulatory Documents
  • NCCLS Documents and Presentations
 
 

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